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Top Questions and Answers
Should I continue taking Toprol XL (Beta Blocker) or discontinue? Eight years ago I went to the ER for atrial fibrillation and a high heart rate (around 180bpm)... the onset was sudden but not the first time... after two days of intravenous dosing of beta blocker meds and TWO cardio versions, I was still in Afib. Then suddenly, like the 3-4 other times it happened at home, all went back to normal. I do not have and never had high blood pressure, just a slightly higher than average heart rate (75-85 bpm) and a sensitivity to MSG, artificial sweeteners and big doses of salt... all of which will cause my heart to beat funny even while taking toprol xl. I was told never to stop taking the med for any reason... then my mom who's on it for a heart attack, was told to stop taking it for 48 hours prior to some testing they wanted to do on her. After 2 days of no toprol, her blood pressure was NORMAL... when any other time it has always been higher while taking toprol xl. I need to know if I'm making things worse or what. I don't like toprol... it's always affected me in ways I don't like... so if I don't need to be on it, I don't want it. Of course my doc says I have to be on it from now on... and other docs say it shouldn't be taken long term. Does ANYONE know the truth about beta blockers, metroprolol xl? I was taking 50mg of Toprol XL for the eight years I've been on it... now two days in to tapering off, I'm at 25mg per day... I've noticed a heightened sensitivity to sound, visual stimulation and some long forgotten memories pop in my head... other than that... steady rhythm, regular pulse (85-95bpm)... nothing out of the ordinary. Actually I feel MORE calm that average... my doc has me on Klonopin 1mg daily for anxiety (he attributed) from the Toprol. By what Dr. Guess says, I'll stay on 25mg for a week, then down to 12mg next week... then off and see how I feel. The only other thing I take (started 3 weeks ago) is L-Dopa 32mg OTC variety... seems to quicken pulse for a few hours then resumes to normal and calmness, lowered voice as well (thought that was odd). I should also add that my doc suggested I could "just stop taking it altogether" if I wanted... I'm tapering anyway... cold turkey after 8 years sounds to me, risky, but maybe not (at 50mg a day anyway).

cowboydoc replied: "You say "doctor" do you mean a family doctor ? go to a cardiologist and have a complete make up run. The accept his advise. And, in what ways don't you like that they affect you."

Ryan J. McCulloch replied: "From you calling it 'Toprol-XL' I can tell you're in the USA, this helps with my advice since medications vary in different countries. Side-effects of Metoprolol include nausea, dizziness, light-headedness, vision problems and diarrhea. If you're suffering all of the side-effects and the cons outweight the pro's then you should see your Doctor and ask to switch to another beta-blocker if you need to take them. I can't tell if you definitely need beta-blockers because I haven't seen your test results so your Doctor is who you need to see. Ask him if you could switch to another like Acebutolol or Esmolol. Hope I helped, Ryan"

Jared replied: "Metoprolol is nothing special. I really don't understand all the fuss about such a medication. It works with the Beta1 receptors. It is very predictable -- Aside from a secondary use of performance anxiety reduction, it is used primarily for hypertension. Not Atrial Fibrillation -- You said your heart rhythm went back on its own and stabilizes (I assume) in that you are no longer in atrial fib at the moment or have been. Regardless, this medication does little if anything at preventing or stopping the fibrillation. It works by reducing cardiac output, reducing heart rate (pulse), and heart contractility. These effects contribute to its blood pressure lowering abilities. It has a short half life, meaning you need to dose it several times a day to prevent rebound effects and just as importantly allow it to stay at balanced serum levels for maximum effect. Which is why you are given the slow release version .. for convenience. :) This isn't the king of beta blockers, but in the preparation you have it isn't a bad choice for HYPERTENSION. They dosed you with betablockers during your afib in the hospital more because of your tachycardia - fast heart rate.. In lowering such a high rate, .. it helps with the sinal impulses in that particular heart node to mediate atrial fibrillation. The medications of choice for Atrial Fibrillation would be (and I'm sure you got this..in the hospital) is - anti arrhythmic. Such examples are: Cordarone, Norpace, Tikosyn, Tambocor, Rythmol.. etc. There are quite a few. These work by slowing your heart rate, and working on the sinus node as referred to before. Some really concentrating on the A/V node. Basically without explaining why this happens (because you probably know all of it already) -- they work on the heart tissues and the electrical impulse action and reactions in the heart to reestablish normal rhythm. Sort of like a liquid pacemaker until the heart 'switches back on its own to this rhythm'. Often people with atrial fib never switch back. In these cases they will either opt for a pace maker or depending on the severity of the afib, age, and other co-morbid factors they will opt for medication. Anti arrhythmic meds as explained before. If these work,.. then they are preferred over such a device implant. I have seen both kinds of patients whose heart will regulate with simply medications, and others whom rhythm will flip flop constantly with tachy and brady occuring concurrently -- that medications just have zero effect on. Some of these people don't have any negative effects from their afib and we just monitor.. most are fitted for some type of device or allowed to continue to try various AA meds to see if things will improve over time. With you -- the only thing that worrys me slightly is the Sinus node occaisonally getting out of wack. IE: You developing transient atrial fibrillation. The elevated heart rate is highly common in afib,.. with the combination of the emergency room, people acting fast and moving about, your own nervousness , and so on. The heart is trying to restablish normal rhythm .. believe it or not the high heart beat is part of the body's own built in reaction to reestablish this rhythm. But the body over compensates, naturally,.. But you say your rhythm like the other few times it has occurred goes back to a normal rhythm and stays there. *if* your rhythm has stayed non afib for years at a time.. then this is what I would do. You are most likely getting a dose of 150-400mg's daily. You cannot (or shouldn't) reduce the medication suddenly , or cold-turkey shall we say. You will need to reduce it slowly over several weeks. A titration downard. If you have some of the non time released version it would be somewhat easier.. but you can break the time released versions of this medication and not lose the time released action. I would recommend starting by breaking it into quarters -- Reducing a quarter the first week. (Taking 3/4's dose for a week). 2nd week, reduce another quarter -- stay on half a pill. 3rd week, stay on the half.. 4th week, reduce to one quarter -- 5th week -- Stop completely. Sounds tedious but needs to be done. There is rebound hypertension, elevated heart rate, increased contractility and so on that can and likely will occur because your body has adapted to the medication. What is key during all of this -- Have an accurate Blood pressure monitor. -- Monitor several times a day every day. Use a legal pad, or some sort of log, to write down your readings each time... note the date, the time of day, the systolic and diastolic readings.. and in your case note the pulse (heart rate). If at any time your blood pressure exceeds 140/90 continue to retake the pressure in a seated or laying down position. If it does not go down re-up your dose slightly to stabliize the pressure. if it is reading 141/92 or so... it isn't anything major.."

JennyH replied: "You never want to stop taking medicine, with out your doctors consent. With your mothers situation, her BP was normal, because the Toprol is still in her system. My father stopped taking his meds, because he said he felt better, his chol. wasn't high neither was his BP. Well....that resulted in 2 heart attacks within two months...a couple months after he quit his meds. I would speak with your physician...maybe there is another drug out there that will suit you better. My father is on Toprol...and hasn't had a problem with it. But, before doing anything, please discuss it with your cardiologist."

Is there a way to stop Toprol-XL safely? i want to know is there anyway to discontinue taking toprol-xl without any problems

zeldaslexicon replied: "Beta-blocker medications such as toprol need to be discontinued slowly and under a doctor's supervision to avoid potentially serious side effects."

sdg-FNP replied: "First, let me suggest that this question is best suited to be answered by the person who prescribed it. Before you decide to stop anything, at least give your provider the benefit of asking for assistance, or telling them WHY you are intending to stop this medication. Likewise, it would be negligent of ANYONE on this forum to tell you how to discontinue a medication that your provider has given you. I prescribe this medication quite often, and know what it's used for. So there's likely a condition that you have and you need to take it. Call your provider in the morning, and talk to him or her. That's the best and ONLY advice you should receive. Best regards."

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