Insulin Resistance Glucophage Diet Posts

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What drugs, other than Metformin/Glucophage, are used to treat Insulin Resistance? I am slightly insulin resistant with normal blood sugars and other lab levels. I did not tolerate Metformin and my endocrinologist told me to stop it immediately. What other drugs are used to treat this condition? (And yes, I am aware diet and exercise are important components of treating this disorder and have already incorporated that part of it into my lifestyle.)

Tin S replied: "Its a shame you can't tolerate Metformin. Its the best drug around for insulin resistance. Your other choices are Actos or Avandia. The "glitazone" diabetes drugs Actos and Avandia may double or triple the risk of broken bones after a year or two of use. The finding comes from Swiss researchers who analyzed 12 years of data on U.K. diabetes patients. They compared the 1,020 patients who suffered some kind of fracture to 3,728 matched patients who did not break any bones. Related to diabetes diabetes symptoms, hypoglycemia, type 2 diabetes, gestational diabetes, diabetes diet, type 1 diabetes, low blood sugar , glucose, insulin resistance, diabetic neuropathy, A1c, exercise and diabetes 2008 WebMD, Inc. All rights reserved. Over the course of the study, most of the patients took several diabetes drugs. But those who refilled their Actos or Avandia prescriptions eight times or more -- about 12 to 18 months of use -- had nearly twice the fracture risk of other patients. And those who refilled their Actos or Avandia prescriptions 15 times or more -- two or more years of treatment -- nearly tripled their risk of fracture, found Christophe R. Meier, PhD, head of pharmacoepidemiology research at University Hospital Basel, Switzerland, and colleagues. "We found a very strong signal here for higher risk of fractures in people taking glitazones," Meier tells WebMD. "Our evidence fits together nicely with animal models and clinical reports suggesting that these drugs have a detrimental effect on bone. And we did not find any increased risk for other diabetes drugs, so all together, it looks like something really is going on here." (What does your doctor have to say about these risks? Talk with others on WebMD's Type 2 Diabetes Support Group message board.) Animal studies reported late last year strongly suggest that Actos and Avandia promote bone loss. Signs that women taking Avandia might be at increased risk of upper arm and hand fracture last year led the drug's manufacturer, GlaxoSmithKline, to voluntarily issue a letter warning doctors that Avandia might increase fracture risk. Good luck"

sue replied: "There are 6 classes of oral drugs to treat diabetes. You have to read about them, so go here and read: Then there are 2 classes of injectables including insulins."

SZO replied: "A newer drug, exenatide (marketed as Byetta), is being used as another alternative to metformin. It has not been approved except for use in diabetics, but often improves insulin resistance by the same mechanism as it does diabetes."

Insulin Resistance Diets? I have just recently found out that i am insulin resistant. My doctor put me on high amounts of glucophage, and told me to lose some weight. He told me to stay away from pasta, potatoes, carrots, rice, white bread and switch to whole grain breads and pastas and also to eat fiber one cereal. He also told me to up my fiber intake and lower the carbs. Im interested in finding a site with an easy to follow diet that is inexpensive and that is fullfilling. This was quite a shock to me but I also know that I have people in my family that are insulin dependant diabetics. Im kinda scared that this is what I will end up with. Does anyone know of a good diet and exercise program? The exercise must be something that i can easily do and tolerate since i have a bad back and have a rod in the spine.. kinda keeps me from doing certain things! I like to walk alot but thats about it.

huggywell replied: "Diet first, google the GI Diet by Rick Gallop. It was initially designed for people with syndrome X (pre-diabetes) and for diabetics. Its easy to follow and healthy. I have been on it for 6 months since I was diagnosed diabetic. I have lost 80lbs and I am now off all the diabetic medication I was on at the start when I was first diagnosed. Forget about exercise programmes, just walk. Its brilliant exercise. Get a pedometer and build up gradually to the recommended 10,000 steps a day. I did that and it helps control so much. Blood test regularly and watch you are no going to low as you lose weight; Good luck. If you need any extra advice look at my profile details;"

Bill Handle replied: "Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat. O'Leary VB, Marchetti CM, Krishnan RK, Stetzer BP, Gonzalez F, Kirwan JP. Schwartz Center for Metabolism and Nutrition, Case Western Reserve University School of Medicine, Cleveland, OH 44109-1998, USA. Exercise improves glucose metabolism and delays the onset and/or reverses insulin resistance in the elderly by an unknown mechanism. In the present study, we examined the effects of exercise training on glucose metabolism, abdominal adiposity, and adipocytokines in obese elderly. Sixteen obese men and women (age = 63 +/- 1 yr, body mass index = 33.2 +/- 1.4 kg/m2) participated in a 12-wk supervised exercise program (5 days/wk, 60 min/day, treadmill/cycle ergometry at 85% of heart rate maximum). Visceral fat (VF), subcutaneous fat, and total abdominal fat were measured by computed tomography. Fat mass and fat-free mass were assessed by hydrostatic weighing. An oral glucose tolerance test was used to determine changes in insulin resistance. Exercise training increased maximal oxygen consumption (21.3 +/- 0.8 vs. 24.3 +/- 1.0 ml.kg(-1).min(-1), P < 0.0001), decreased body weight (P < 0.0001) and fat mass (P < 0.001), while fat-free mass was not altered (P > 0.05). VF (176 +/- 20 vs. 136 +/- 17 cm2, P < 0.0001), subcutaneous fat (351 +/- 34 vs. 305 +/- 28 cm2, P < 0.03), and total abdominal fat (525 +/- 40 vs. 443 +/- 34 cm2, P < 0.003) were reduced through training. Circulating leptin was lower (P < 0.003) after training, but total adiponectin and tumor necrosis factor-alpha remained unchanged. Insulin resistance was reversed by exercise (40.1 +/- 7.7 vs. 27.6 +/- 5.6 units, P < 0.01) and correlated with changes in VF (r = 0.66, P < 0.01) and maximal oxygen consumption (r = -0.48, P < 0.05) but not adipocytokines. VF loss after aerobic exercise training improves glucose metabolism and is associated with the reversal of insulin resistance in older obese men and women. PMID: 16373444 [PubMed - indexed for MEDLINE]"

Insulin Resistance? I have just been diagnosed with IR- I was put on the medication Glucophage. My dr is trying to keep me from becoming a diabetic. I know I have to excersise more and change my diet. I need info on a good low carb diet to follow. Any suggestion swould be greatly appriciated. I am also hoping this is the reason we have been having trouble concieving.

lampoilman replied: "I didn't know that WE were trying to conceive...funny, you would think that I would remember something like that. As far as the diet- Google it. There are HUNDREDS on line and one will work for you."

zippythejessi replied: "Look into the South Beach Plan. It teaches you the proper carbs - i.e. whole grains, fruit, and veggies vs. refined stuff. (white bread, etc.) It's not crazy like Atkins, I think it's more sensible - once you get past the first two weeks. If you read the first book (the green-covered one) he emphasizes the need to read labels on anything packaged and to try to eat the fresh stuff as often as possible. At least, that's what I got out of it. Good luck!!"

Sabz replied: "I would recommend South Beach diet as well. While it starts out similar to Atkins, after the first two weeks it emphasises whole grains, fruits and vegetables, and not as much red meat. Also, make sure you take your glucophage at the same time every day, and on a full stomach. Changing the timing could make you jittery if your sugar drops too much."

ringocox replied: "The best plan is to go to the dietetic department of the nearest hospital and pay a dietitian to prepare a diet for you. She can give you the proper calories for your weight and activity and balance it to suit your likes and dislikes."

chocolatelover replied: "HAHAHHAHAHAH. Oh my love, You WILL conceive on Glucophage. Absolutely. Glucophage is being used by fertility specialtists with alot of success and without multiple births. But remember, you will be put on insulin while pregnant if you are diabetic. Inject close to the belly button, hurts less. HAHAHAHA. Talk to you in nine months. I'll just say congratulations now. HAHAHAHAHA :) :) :) :) :)"

rxstudent01 replied: "I would follow a diet that is approved through the American Diabetic Association, they know what they're talking about."

mombolita replied: "Could be that you have polycystic ovary syndrome - PCOS. PCOS women have increased risk for IR and diabetes and difficulty conceiving. The Glucophage is used to treat both IR, DM and PCOS. Are you seeing just your PCP or an endocrinologist or endocrinology-fertility specialist? You need either an endocrinologist or e-f specialist at this point. If you have never been tested for PCOS, you should be! Good luck. PS: see a certified diabetes educator and/or dietician for best advice! try this link: "

Lia replied: "First of all, the best treatment for insulin resistance is exercise. And exercise doesn't have to be drudgery! (I like to work in the yard) Weight training will boost your metabolism quickly and good-ole-walking will help you lose weight. If you are able to lose 10-15 lbs. you will greatly reduce your risk for type II diabetes. As for the diet, just avoid sweets and foods that are white. (sounds weird, but think about all we eat that is white and fattening!) The best rule of thumb is.... Make BIG changes in your activity level, and make SMALL changes in your meal plan. If you follow this adage, you are less likely to binge and give up early. There are great support groups out there like Overeaters Anonymous, Weight Watchers, and TOPS. Good Luck!!! It's up to you to make your body the best it can be for your unborn child."

ninamcguinness replied: "Insulin resistance is a pretty common phenomenon these days. For myself, I have Polycystic Ovarian Disease, and one the conditions associated with it is insulin resistance. The medication of choice is indeed Glucophage, so your doctor is on the right track. The American Diabetes Association has a food guide which you can use to help you on your way.(I am Canadian, and I use the CDA guide). They breakdown the amount of carbohydrates in various different foods, so it becomes very easy to follow. Good Luck to you and I wish you the best."

Are there alternatives to glucophage? I have pcos with the insulin resistance but the glucophage makes me sick to my stomach every day. It also is not helping with any weight loss even combined with diet and exercise. Is there anything else that can be taken to control this? I'm going in to the doctors in 2 weeks to discuss a plan of action to help with the weight and help with getting pregnant and would like ideas beforehand to discuss with her. Any advice/help is appreciated!

jennanderton2006 replied: "ask your doctors"

Kristi replied: "A lot of women (myself included) get upset stomachs while taking gluphage. I found that if I eat something when I take it I don't have as much stomach problems. I also found that foods high in sugar/starch and fat aggravated the problem and made the problem worse. You can try following the PCOS diet, or the Mediterranean diet. Both these diets are based on low glycemic index foods, and have been proved to help with insulin resistance. You can find more information about pcos at. I wish you lots of luck with your treatment."

Z H replied: "glucophage is the only diabetes med that can help with both issues. Wt loss also helps with both. Also watch for subclinical hypothyroidism. There are alot of diabetes treatments Bietta is a very exciting one because of the weight benefits."

navyprincess1227 replied: "From my understanding, there is only Glucophage/Metformin for PCOS/IR. Are you taking the XR? You could talk to your dr about lowering your dosage. I was taking too much and that caused me to not loose much weight, but I was more concerned with getting pregnant than loosing the weight while I was on it."