does this make you loss hair? Nizoral Nizoral is an anti-fungal shampoo that kills the fungi that cause seborrhea and dandruff. Groups of individuals have discovered that Nizoral (when used regularly) is a very useful alopecia treatment, once again it would appear that the role of a substance for the treatment of hair-loss is stumbled upon accidentally! Nizoral contains a chemical called ketoconazole, it is known that when ketoconazole is ingested orally that it inhibits the binding of androgens to receptors in the body and this would include the binding of DHT to hair-follicle receptors. However the use of oral ketoconazole is NOT recommended for many reasons, mainly because this method would present itself as a toxin and ultimately damage the liver. But topical ketoconazole (as contained in Nizoral shampoo) shows itself to have a "weak" anti-DHT binding affect in the scalp. Furthermore positive results with Nizoral shampoo are often noted within a few weeks, whereas a pure anti-DHT affect may take a few months. It is therefore likely that Nizoral exhibits another method to its anti-hair-loss effect. One such theory of Nizorals anti-alopecia effects may be on its activity upon sebum. Sebum is a fatty substance that accumulates in the scalp around the hair follicles. Its possible that the removal of sebum may help "unclog" the hair follicle and expose it to more nutrition from an improved blood supply, rather like unclogging a drain! It is known that Nizoral can remove and reduce sebum deposits man im scared to used this stuff, i got some weird fungi like stuff around my neck and its nasty and dry and the doctor prescribed me this and ketoconazole cream, and im scared to use the sh*t because it makes your hair fall out!! im only 18 i aint going bald over some dumb sh*t!