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Of the two Lexapro or Cymbalta, which generally has less sexual side effects? Lexapro being the most 'selective' SSRI and Cymbalta being an SNRI

Melissa B replied: "Lexapro: Common side effects: Dermatologic: Diaphoresis Gastrointestinal: Diarrhea, Nausea Psychiatric: Sleep disorder, Somnolence or insomnia Reproductive: Disorder of ejaculation, Impotence Other: Fatigue Serious side effects: Endocrine metabolic: Syndrome of inappropriate antidiuretic hormone secretion Psychiatric: Depression, worsening (rare), Suicidal thoughts (rare), Suicide (rare) Cymbalta: Common side effects: Cardiovascular: Palpitations (1% to less than 10% ) Dermatologic: Diaphoresis (6% to 8%) Gastrointestinal: Constipation (5% to 15% ), Decrease in appetite (6% to 16% ), Diarrhea (7% to 13% ), Nausea (14% to 38% ), Xerostomia (5% to 15% ) Musculoskeletal: Asthenia (2% to 8% ) Neurologic: Dizziness (6% to 17% ), Insomnia (9% to 13% ), Somnolence (7% to 21% ), Vertigo (1% to less than 10% ) Ophthalmic: Blurred vision (1% to less than 10% ) Renal: Increased frequency of urination (1% to 5% ) Reproductive: Reduced libido (1% to 7% ) Respiratory: Cough (3% to 6%), Nasopharyngitis (7% to 9% ) Other: Fatigue (2% to 13% ) Serious Side effects: Hepatic: Hepatotoxicity Psychiatric: Suicidal thoughts (4% )"

facestank replied: "Hard to say, because there is a lot of variation in the side effects, depending on the individual taking the medication. But, I would guess that Cymbalta is more likely to have worse side effects because it is an SNRI, so it works on more neurotransmitters than Lexapro (which is an SSRI). Lexapro is marketed as an antidepressent that has less sexual side effects than others. I still have heard that a lot of people have problems with it though."

Q.T. Reuben 2 replied: "I took Lexapro for several months last year. While it didn't take away my desire or ability it did take forever for me to ejaculate. I didn't have an orgasm, just a feeling of relief similar to emptying a full bladder."

The Kings replied: "Cymbalta turned me into an insane bitch 1-2 hours after taking it, and then it would ease up. It also made me sick right after taking it. Lexapro, on the other hand, doesnt have any side effects for me. Not even sexual ones ."

How to treat Borderline Personality Disorder, ALONG with therapy? What are other treatments available (medications) that are commonly prescribed to reduce the symptoms of BPD? I've tried SSRI's (Zoloft and Lexapro) and SNRI's (Effexor XR) but it didn't affect me at all. I gave each drug a chance for 3 months each, but I didn't get any relief. I'm in therapy, but it's not helping with my suicidal thinking. I need something that will reduce my impulsive and reckless behaviour and anger/irritability. I can't be on something that is easily addictive, because I've been known to abuse drugs and have been hospitalized many times. Please help me. Does anyone else here have BPD? What has helped you?

myheartisjames replied: "wellbutrin helped me... but what helped me most was THE RIGHT kind of therapy... Dialectical Behavioral Therapy...in which i learned skills to help make my life better... if you read my profile you'll see that while i am still plenty mentally ill...i do not have BPD anymore... i still meet about 3 or 4 out of the symptoms..but not the whole 9 anymore.... Dialectical Behavioral Therapy is the most widely known help available...... talk therapy doesn't really do much for borderlines.... traditional therapies do not really do much for borderlines and psychoanalysis can be particularly bad for borderlines.... DBT is a form of Cognitive Behavioral Therapy.... (CBT) but still DBT has been proven to be far more beneficial.... DBT was created by Marsha Linehan... just google her and find her website... you can even call her office and ask if there is a DBT therapist in your area... the only drawback is that DBT therapy can be hard to find... more and more hospitals are using it these days which is good..but to find an individual practitioner can be hard.. i was very lucky...and i will always thank Norma Albanese who was my DBT therapist.. she helped me more than she will ever know..... good luck! i wish you all the best..... BPD is hell to live with.... ps...i was hospitalized three times for BPD....but i have managed to avoid the hospital for years now....... i have gotten bad enough that i needed to be in it...but...i have made it through those episodes and come out all right....."

michelle_wont_tell replied: "Lamictal along with Effexor XR is a great combo for some. But it all depends on the severity of your condition and how your body responds to the drugs. Good luck"

Jesika replied: "I have a past Dx of having BPD (along with many other Dx) -- today I am virtually free of all symptoms. It takes a great deal of patience. I found that integrating many forms of therapy together helped the most - CBT, DBT, expressive therapies were very helpful as well. I have also been on alot of meds in the past - medication is difficult because everyone has a different chemical makeup - so what may work well for one person, may be toxic to another. Also, just like any type of "drug" - we can build up a tolerance - which is why it's important to not start/stop medication often. It makes finding the right one/ones more difficult. Personally, I found the most helpful meds to be Cymbalta, Seroquel, Abilify, Risperdal, and Buspar. Talk to your psychiatrist, and do your own research too. I would research into some IOP programs that specialize in DBT, in a group setting. There are also good books & workbooks on BPD. "Mind Over Mood" is a great one. Some other good ones are "Borderline Personality Disorder Demystified: An Essential Guide for Understanding and Living with BPD" by Robert O. Friedel, Perry D. Hoffman, Dixianne Penney, and Patricia Woodward, and also "Don't Let Your Emotions Run Your Life: How Dialectical Behavior Therapy Can Put You in Control (New Harbinger Self-Help Workbook)" by Scott E. Spradlin (Paperback - Feb 2003) all of which you can order at amazon.com And ofcourse in order to let go of one behavior (destructive) there has to be something to put in its place (constructive). Best of luck to you!"

Any supplements or drugs I can take to cure my lack of motivation? I take lexapro and it dulls my motivation and seems to make me have less energy. Anything to counteract this? I do not want to take SNRI's b/c they screw me up bad.

People who've switched from SSRI's to SNRI's, how's it been? Currently on Citalopram (Celexa), but mildly tired. If I don't get perfect sleep, exercise, and perfect eating, I'm wasted tired. Lexapro, another SSRI, was the same for me. So....have thought about SNRI; scared off a bit by the high dosage required, and also by the idea of switching meds at all. 'Try' out too many meds, your brain fries I think. Just like try out too many drugs, you end up like Bob Dylan or Osbourne: fucked. So....if you have stories about your transition, please tell. Thank you

Mad Mac replied: "SSRI's and SNRI's both have definite problems with withdrawal. In switching you might find some symptoms of withdrawal since the drug chemistry is different. For more personal opinions on SNRI"s just type "SNRI's" into Yahoo! web search and a number of forums with comments comes up plus other info. For more technical info go to "Selective Nor-epinephrine Re-uptake Inhibitors" on Yahoo! web search. Yes, drug effects on the brain are a worry. I took Sertraline for years (an anti-psychotic) and developed irreversible Tardive Diskonesia (Parkinsonism like tremors). Benzodiazapines have proved to be addictive. The FDA has been very lenient in granting licenses to pharmaceutical manufacturers and don't require rigid testing for long term side effects. They really can't because it may take a lifetime for some effects to develop. Good luck, good health, peace and love!"

Jess replied: "I don't think it fries your brain to try different meds. It's kind of the rule rather than the exception...finding the right medication (s) is trial and error. Recent research indicates that some psych meds actually result in an increase of neurons (brain cells)...which means they are sort of doing the opposite of frying your brain. On the other hand, it's true that there is not sufficient data regarding the long term use of most psych meds. I've been on SSRI's and an SNRI and had similar results with both. They did work but they aso had sexual side effects that led to me going off of them and trying something else. I'm bipolar and will most likely need medication for the rest of my life if I have any hope of having any sort of stability. Learning as much as I can about meds and brain functioning has become a bit of an obsession for me the past few years."

Klonopin (Clonazepam) & Effexor XR Anyone on SNRI & Benzo? Panic Disorder Depression AnxietySocialAnxiety HELP? Thanks for stopping by, this could be kinda long but it's important and I put detail into it.. Just incase you don't already know?: EFFEXOR XR is a prescription antidepressant and is indicated for major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. CLONAZEPAM/KLONOPIN is a prescription used for : Controlling certain types of seizures in the treatment of epilepsy and for the treatment of panic disorders. It may also be used for other conditions as determined by your doctor. Clonazepam is a benzodiazepine. It works by increasing the activity of a naturally occurring chemical in the brain. (I'm a {}male {}20 years old) - Diagnosis: {}Panic Disorder {}Clinical Depression {}Social Anxiety - Medicines I've tried {}Lexapro {}Celexa {}Paxil {}Abilify {}Buspar {}Ativan (And of coarse {}Effexor XR & {}Clonazepam (Klonopin) - Went to Doctor, then community mental health clinic, now I'm at a much better place then the mental health clinic Seeing a psychologist and waiting to see the psychiatrist Until I can see the psychiatrist at the new place I'm going I went to a different doctor (who accepts Medicaid) and explained this all to him - I was on effexor xr 75 mg for about a year+ (which my doc told me is an ineffective dose, the therapeutic dosage for Effexor XR is at least 150-300) -And also on Klonopin (Clonazepam) .5 mg 2x daily - I was on both (Klonopin& effexor xr) for about a year up until December of 2008 -I no longer had insurance and decided to try going without any medicine for awhile, and there wasn't a way to "taper off" without insurance, so i stopped both cold turkey (please no comments on how that's not good.. i know) However I made it through getting off of these medications and it wasn't as bad as everyone said. - Since going off of these medications my panic/anxiety & depression has peaked - So like I said I went to a doctor until i can see the psychiatrist -He suggested I try going back on effexor only at a therapeutic dose Below is the treatment plan for now read and discuss after: Effexor XR 37.5 mg (they want to ease you up so they give you 30 pills at 37.5 mg each and say: take 1 for 5 days (37.5 mg/day) take 2 for 5 days (75 mg/day) then take 3 for 5 days (112.5 mg/ day) Then I can get a script filled for 150 mg Effexor XR The 150 mg should start to help the panic, social anxiety, gad, & my depression In combination with the Effexor XR; I will start back on *Clonazepam* 1 mg 2 times per day *(PS: I know clonazepam is a controversial drug and may have withdrawl effects but for the benefits of functioning way outweigh the risks. So no comments on that please)* The 1 mg Clonazepam twice a day should help control my anxiety and panic In addition to those medications I'm already seeing a psychologist, I believe talk-therapy alone isn't the cure but I'm hoping medicine and the talk therapy will be beneficial together. In your answers you can leave advice comments etc, just no lectures or anything like that thanks. Also If you do take these medications (esp. together) leave you experience/progress Any advice on what time you take Effexor XR (currently taking it in the morning) Clonazepam/Klonopin (currently taking not specific times, but twice a day) answers(/anything you have to add) I receive is appreciated

minx replied: "wow, i'm speechless ......... go and get yourself fully assessed by a naturopath or other wholistic healer ....... get them to do testing for food allergies/intolerances and chemical sensitivities .......what you ingest and absorb through your skin and breath can have a vast impact on the way you think, the way you feel and your overall health and vitality ....... seriously, you can live a pain free drug free life if only you know precisely what chemicals and foods are upsetting your system .... it could be something as simple as lactose intolerance or an intolerance to processed sugar or wheat ...... disorders from which people suffer due to intolerances to food or chemicals in their diets can cover almost the whole spectrum of physical and mental illnesses ..... an extraordinary concept but mind blowingly true....... do yourself a favor and go and get allergy tested. in the meantime, try to eat as much whole fresh foods that you prepare yourself that includes a wide range of leafy and green vegies, some low sugar fresh fruits like watermelon, cantalope, pears and strawberries, some lean meats and fishes, brown rice, organic nuts and seeds like almonds, brazil nuts and sunflower seeds and lots of fresh filtered water .......... ditch the sodas, pop and soft drinks, consumption of foods containing processed sugar and junky and take away highly processed foods ...... ** and that includes alcohol** ....... not immediately of course or the detox would be too nasty ...... slowly ...... and feed your body from God's table and wean yourself off the highly processed, packagedsludge that has little to no nutritional value anyway. i was diagnosed with "Bipolar/Schizophrenia" 7 years ago and was pumped to the eyeballs with a selection of very heavy antipsychotis and large amounts of Effexor daily (600mg) ....... by taking all their nasty meds i ended up an insomniac, with achy bones, nasty sweating, headaches and migraines, terrible mood swings, permanent constipation, constant sweating ......... until i got reassessed by a naturopath and was diagnosed coeliac, lactose intolerant, intolerant to soy and processed sugar and a plethora of other preservatives and other nasty chemicals they use to preserve our foods......... it wasn't a mental illness at all with me .... it was all food and chemical intolerances ... i detoxed off the meds and cleaned up my diet and finally got me the bounce and vitality back that i'm entitled to ....... that we're all entitled to. EDIT: sorry, i should clarify that i'm speechless at the fact that physicians are so ready to simply continue to prescribe such meds on a never ending basis when they clearly aren't resolving the problem ...... perhaps your health issues need to be resolved from the source mate, not bandaided with toxicmeds. peace baby "

mntnrain80c replied: "I used to have severe panic/anxiety attacks and depression I took clonopin and paxil also went to talk therapy which helped I also had severe agorophobia and had to go to day treatment which is kind of like a babysitting service for people with mental illness. But after going there for about 2 weeks I noticed that there were so many people who had wasted their life by going to this place. It seemed that they bought into the whole "you're ill and you can't decide things for yourself type stuff) I quit going there and I decided I would make myself go out and do things even if it was just baby step type things then push to do more and more. After all this is the type thing that no one else is going to make go away you have to reach deep within yourself to find the strength to over come it. I eventually weaned myself off meds and started driving etc also got a job and have had no problems (well major one) since If I feel anxious I ask myself what is causing it and then work to calm down. Breathing, meditation etc works wonders. I also have the attitude now of I don't care what people think That used to be one of my fears I was afraid if I had a panic attack in public I might start acting irrational and be embarrassed. I could write volumes on panic/anxiety disorder but the space here is limited if you want genuine help then feel free to write me using this screen name @ yahoo.com And no I'm not going to tell you to find Jesus etc That's a choice people have to make on their own and when I was at my worst I would get so annoyed at people who tried to tell me I was being punished for so un named sin etc. I just offer you a friendly compasionate person to talk to about this."

underdamped replied: "Ah, the nay-sayers. Medications have saved and improved so many lives. They not be the right thing for everyone, but I am a firm believer in modern science... Ok, I have depression, bipolar, panic, and add, here's the list: AM 300 mg wellbutrin xl 300 mg lamictal 200 mg provigil 60 mg strattera PM rozerem 1 mg klonopin 37.5 mg paxil as needed: klonopin, niravam (super fast-acting xanax) I sleep. I'm healthy, my nails, hair, and skin are beautiful. I take dance and martial arts and am in the best shape of my life. I'm taking classes (18 units) to get ready for a master's degree program, I study like 8 hrs/day, and I get good grades. etc. I agree with you 100% - the benefits of *functioning* far outweigh the risks/side effects. 50 happy years are better than 80 miserable ones. yes, I take a ton of medication. it not only saved my life, it took it from hell to good. Find a good psychiatrist and be patient. It took a year to get my little cocktail just right, it sucked, but I'm finally mostly normal. Yep, you gotta have therapy too. You need coping skills to deal with that occasional...symptom. I have found that I can handle life better than most healthy people, every-day problems are so small compared to things I have experienced. Even if I could, I wouldn't "heal" myself. I have become very compassionate and non-judgemental. I believe I am better for it and so are those around me. (FYI I'm an athiest) Hope they figure it out for you. And I hope it doesn't take too long. Chat with me anytime, especially if the nay-sayers or people who think it's all in your head get to you."

underdamped replied: "Sorry, I wrote the answer above and then realized I had to change my account and settings, etc. if you want to msg me, it's underdamped_2 :)"

Margaret P replied: "Get as much resource as you can maybe is one option,however it could be quite time consuming,here is one resource i have had good experience."

Pico replied: "I take 300mg Effexor XR, 2mg of klonopin and 30mg of Abilify. I'm diagnosed with 'major depression with psychotic features', GAD and PTSD. I'm 31, been suffering with this crap since I was 12 but was not diagnosed until I was 28. I'm doing better on this drug combo than on any other meds I've been on. I haven't been on many (Lexapro, Zoloft and Ativan). The Zoloft did nothing at all for me and I took 200mg. The Lexapro was a bit better but nowhere near good enough. Ativan was a nightmare. It helped with my anxiety and panic disorder but I got addicted to it within weeks. I was popping the pills all day long. I was switched to klonopin and have had no problems with addiction and it works GREAT for my anxiety. I haven't had a panic attack in over 2 years. Honestly, I take my meds when I remember to take them. I used to be really good about taking the Effexor at night but lately I fall asleep before I remember to take it. I end up taking it at all hours of the day and it doesn't seem to effect me in any negative way. I originally chose to take it at night in case it made me sleepy. I'm supposed to take 1mg of klonopin in the morning and 1mg at night. I take the Abilify with the Effexor whenever I remember to take them. Klonopin is a long lasting benzo. It was explained to me that it works slowly but stays in your system for a long time. It's best to take it on a schedule and space it out. When I was on Ativan, it was 'take as needed'. It's a fast acting benzo. It hits you hard and wears off the same way. It would wear off suddenly and I'd be hit with anxiety and need another pill asap. That's how I got addicted. As for progress, I had a psychotic breakdown in July 2006. I got on Lexapro, Ativan and Abilify right away. As I said above, the Lexapro and Ativan didn't work out for me. I got on the Effexor and klonopin around Feb 2007 and it's done nothing but good things for me...mostly. My sex drive has been a LOT lower since I've been on these meds but I can handle that better than wanting to kill myself. One of the meds gives me night sweats. It's not every night and I'm unsure which med is causing it. I'm leaning toward the Abilify though. As for taking these meds together, I haven't had anything negative happen because of the combo. I was feeling a bit lethargic recently and I complained of constant fatigue. My psych put me on Wellbutrin as well but I had a terrible acne breakout after about a week. I can't live with that so I ditched the Wellbutrin. Unfortunately, it REALLY helped to fight the fatigue."

Which is best? TCA Vs. SSRI Vs. SNRI? Which is better for a person who suffers from anxiety primarily, followed by ADHD and, then Depression? and what is really the difference between these. I have found doctors to peddle what they prefer vs. what may suit an individual and this is driving me crazy as each one wants 4-6 weeks before changing and this is becoming a long and really annoying journey. I had best results with Paxil but it did have some nasty side effects (sexual). Now I am on Wellbutrin ramping up to an augment with Adderall, but that still leaves the anxiety piece unaddressed and this concerns me. I keep hearing people rave about Lexapro (Doctors too) and (Effexor) what's the difference. Finally doctors keep telling me that anxiety medications should only be taken for short periods of time (Xanax) but then I find out there are patients who have it as an augment to an SSRI indefinitely so what gives? I know everyone is different but there has to be a general consensus of some sort.

Dr Ben replied: "These drugs work by modulation of a complex relationship between serotinin, dopamine, and norepinephrine, with certain drugs working more strongly one one than others. The exact effects of each drug depend on the patient's own body chemistry and the response to environmental stressors. No one drug is best for one condition in all patients and it often takes several medication trials to find the one medication, or combination of them, that works best for the patient with the fewest side effects. It is true that people are leaning more toward SSRIs and SNRIs as these seem to be more effective in more patients with fewer side effects. TCAs, on the other hand, are cheaper and sometimes just as effective, although the side effects can be higher. Benzodiazepines are avoided when possible due to their abuse potential and the tolerance that develops with long-term consistent use. It may be frustrating as these drugs take a long time to have full effect and cannot be used in certain combinations, but when you find the right medication or combination, rest assured that it usually works for quite some time."

Anyone have generalized anxiety disorder? Which is better for treatment, SSRIs or SNRIs? I've been on three SSRIs (Lexapro, Zoloft, and Prozac) as well as Buspar, Seroquel, and now Abilify. I feel like I should try an SNRI like Effexor or maybe some benzodiazepines. Besides medication, how do you guys deal with it?

cone artist replied: "I use trazodone. To be honest, instead of being constantly worried about things it comes in waves - something at least. I try not to even think about my career or money situation until something is set to change. I just live a reasonable lifestyle, keep doing my job. When promotion or other opportunities arise, then I will think about it. If not, I just dont worry or let it into my head."

Can Effexor XR help with BDD (Body Dysmorphic Disorder)? My doctor doesn't know that I'm dealing with BDD because I'm just to embarrassed to tell him. It is a very disabling illness to me and makes me unable to function in society. My doctor has diagnosed me with social anxiety disorder and prescribed me the Effexor. He doesn't know that my social anxieties have been caused by BDD. Can this antidepressant help treat my condition? Or is there another medication that would better suit my needs? I've done some research only to find out that SSRI's help. And I've tried Zoloft and Lexapro. Effexor is an SNRI so it might help but I don't know and I can't ask my doctor. Anyone know more about Effexor and BDD, or if another medication would be better? I'm on 225 mg of Effexor XR and have been on it for only 3 weeks. Not long enough to know if it will work yet... I know the doctor SHOULD know. But, that's my problem I really just can't tell him. :/ I just need to know if anyone here has had any experience with BDD and what, if anything, had helped.

anxiety medicines...? My Doctor give me both ssri and snri , like in mornning i have to take ssri (Lexapro (Escitalopram Oxalate)) and in night snri (venlafaxine) and Alprazolam for both mornning and night? the real question is taking SSRis and Snris in a day with Alprazolam is alright? thanks and regards

Move on replied: "Dude, you're a walking pharmaceutical add. Lose the drugs, improve your diet, exercise, and get back to nature once in a while."

Medication antidepressant questions. I'm confused.? Thanks! Here are my questions. Answer as many as you know the answers to. Serena I'd like the technical answers when possible: If I'm irritable, angry, have insomnia, less hugnry and more sex drive on Wellbutrin, would adding lexapro, which made me really tired, hungry and no sex drive cancel the bad side effects out? How much of each? Or a different ssri? I have depression and some anxiety in the form of a little ocd and irritability. What usually happens to people if they take an ssri with a ssni like cymbalta or effexor xr? What is the difference between mood stabilizers and anxiety medications? What are the benefits and disadvantages of them? Does Zoloft make most people gain weight? I heard it's the worst for sexual side effects. IS that true? Does Cymbalta and Effexor XR make most people gain weight? Why do some people have side effects from a med but not others on the same med? Please don't just say that everyone's different. Technically, how do antidepressants make you gain weight? Does it change your metabolism? Can I add something to help with sexual side effects? Why do psychiatrists prescibe ssri's first to people before wellbutrin and snri's? What would happen to my side effects from effexor XR if I increased my dose? Would they increase? For example, I'm tired and have no energy on it. Would it get worse usually? Why do antidepressants tend to make people tired and have less energy when that's one of the side effects of depresstion they're trying to help? Why does the same ssri affect peopel differently? Why do meds in the same family of antidepressants, such as ssri's affect me differently (each one) when they all are supposed to help the same chemical, such as seratonin? Why does WElbutrin help some people but not work for me? What is the equivelent of 10 mg lexapro to prozac? What is the equivalent of 37.5 mg of effexor xr to cymbalta?

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