Stephanie replied: "i would of suggested a liver panel test regardless of the medications you'v been on/tried ect..... your symptoms with or without medications indicate something might be causing your issue. sometimes the causative factor hasn't been found yet. something physical causes the chemicals in the brain to react in the wrong way. depression does NOT happen on it's own! there are many diseases out there (viral, bacterial, environmental ect) that have a lot to do with why some are having the issues your having. hcv can cause all of what your experiencing and i can be certain that you didn't list half of what you experience on a daily basis. panic attacks are the WORST! i was misdiagnosed year after year after year after decades....my symptoms started at age 8, by 13 my bones/joints hurt, depression set it ect ect...they only got worse. medications didnt ever really help, unless for false hope as they soon would not be effective. come to find out, i had undiagnosed HCV infection (liver disease). i did antiviral chemotherapy and now the only issue i have is brain fog/short term memory issues. (some things after a chronic illness for so long are not reversable. some think it's a combination of the virus passing the blood brain barrier and all the different kinds of meds i took off and on for over a decade). i can certainly relate and i can honestly tell you that you sound exactly like many others with liver disease out there.... my doctor tried to tell me it was all in my head...year after year....well, it was in my head, but not all of it! hcv does pass the blood brain barrier (as well as other viral infections/agents). it can cause a whopper on the whole body as a whole. do not rely on alt and ast levels alone when you ask the doctor for a liver panel test....alt and ast levels are with many not elevated, leaving the doc to think there isn't anything wrong. have them run an hcv antibody test. if the doctor asks if you have a risk factor for hcv, tell him everyone has one risk factor for hcv...everyone. you dont have to touch drugs, you dont have to have a blood transfusion to become infected with hcv.....dental proceedures, peircings ect....there are many ways for infectious blood to enter the bloodstream of another. last but not least, make the doctor do his job or find someone else until someone wants to do their job! good luck!"